8 citations · 8 across the 4 of their papers we have counts for
4 papers
Correlation between sequence hydrophobicity and surface-exposure pattern of database proteins
Susanne Moelbert, Eldon Emberly, Chao Tang
Hydrophobicity is thought to be one of the primary forces driving the folding of proteins. On average, hydrophobic residues occur preferentially in the core, whereas polar residues…
Finding regulatory modules through large-scale gene-expression data analysis
Morten Kloster, Chao Tang, Ned Wingreen
The use of gene microchips has enabled a rapid accumulation of gene-expression data. One of the major challenges of analyzing this data is the diversity, in both size and signal st…
Flexibility of beta-sheets: Principal-component analysis of database protein structures
Eldon G. Emberly, Ranjan Mukhopadhyay, Chao Tang +1
Protein folds are built primarily from the packing together of two types of structures: alpha-helices and beta-sheets. Neither structure is rigid, and the flexibility of helices an…
Designability and Thermal Stability of Protein Structures
Ned Wingreen, Hao Li, Chao Tang
Only about 1,000 qualitatively different protein folds are believed to exist in nature. Here, we review theoretical studies which suggest that some folds are intrinsically more des…