73 citations · 152 across the 5 of their papers we have counts for
4 papers · 1 filter
Dynamic competition between transcription initiation and repression: Role of nonequilibrium steps in cell-to-cell heterogeneity
Namiko Mitarai, Szabolcs Semsey, Kim Sneppen
Transcriptional repression may cause transcriptional noise by a competition between repressor and RNA polymerase binding. Although promoter activity is often governed by a single l…
Efficient Degradation and Expression Prioritization with Small RNAs
Namiko Mitarai, Anna M. C. Andersson, Sandeep Krishna +2
We build a simple model for feedback systems involving small RNA (sRNA) molecules based on the iron metabolism system in the bacterium E. coli, and compare it with the correspondin…
Genetic Regulation of Fluxes: Iron Homeostasis of Escherichia coli
Szabolcs Semsey, Anna M. C. Andersson, Sandeep Krishna +3
Iron is an essential trace-element for most organisms. However, because high concentration of free intracellular iron is cytotoxic, cells have developed complex regulatory networks…
Structure and function of negative feedback loops at the interface of genetic and metabolic networks
Sandeep Krishna, Anna M. C. Andersson, Szabolcs Semsey +1
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system…