103 citations · 148 across the 3 of their papers we have counts for
3 papers
Mapping the conformations of biological assemblies
P. Schwander, R. Fung, G. N. Phillips +1
Mapping conformational heterogeneity of macromolecules presents a formidable challenge to X-ray crystallography and cryo-electron microscopy, which often presume its absence. This…
Protein structural variation in computational models and crystallographic data
Dmitry A. Kondrashov, Adam W. Van Wynsberghe, Ryan M. Bannen +2
Normal mode analysis offers an efficient way of modeling the conformational flexibility of protein structures. Simple models defined by contact topology, known as elastic network m…
Optimization and evaluation of a coarse-grained model of protein motion using X-ray crystal data
Dmitry A. Kondrashov, Qiang Cui, George N. Phillips
Simple coarse-grained models, such as the Gaussian Network Model, have been shown to capture some of the features of equilibrium protein dynamics. We extend this model by using ato…