258 citations · 475 across the 4 of their papers we have counts for
5 papers
SmartTrap: Automated Precision Experiments with Optical Tweezers
Martin Selin, Antonio Ciarlo, Giuseppe Pesce +10
There is a trend in research towards more automation using smart systems powered by artificial intelligence. While experiments are often challenging to automate, they can greatly b…
DNA Calorimetric Force Spectroscopy at Single Base Pair Resolution
Paolo Rissone, Marc Rico-Pasto, Steve Smith +1
DNA hybridization is a fundamental reaction with wide-ranging applications in biotechnology. The nearest-neighbor (NN) model provides the most reliable description of the energetic…
Single-molecule derivation of salt dependent base-pair free energies in DNA
J. M. Huguet, C. V. Bizarro, N. Forns +3
Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in…
Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured results
J. -D. Wen, M. Manosas, P. T. X. Li +4
Experimental variables of optical tweezers instrumentation that affect RNA folding/unfolding kinetics were investigated. A model RNA hairpin, P5ab, was attached to two micron-sized…
Condensation transition in DNA-polyaminoamide dendrimer fibers studied using optical tweezers
F. Ritort, S. Mihardja, S. B. Smith +1
When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate…