11 citations · 11 across the 2 of their papers we have counts for
2 papers
cs.LG2026
ShallowBench: Benchmarking Generative Drug Design Models on Shallow-Pocket Targets
Saket Reddy, Shiwei Liu
While generative AI models have demonstrated remarkable success in structure-based drug design, they predominantly rely on deep binding pockets and struggle to sample effective lig…
q-bio.BM2023★ 11 cited
Predicting mutational effects on protein-protein binding via a side-chain diffusion probabilistic model
Shiwei Liu, Tian Zhu, Milong Ren +3
Many crucial biological processes rely on networks of protein-protein interactions. Predicting the effect of amino acid mutations on protein-protein binding is vital in protein eng…