114 citations · 183 across the 6 of their papers we have counts for
4 papers · 1 filter
Measurement-limited learning of conformational heterogeneity in cryo-electron microscopy
Henry H. Mattingly, Luke Evans, Pilar Cossio
Cryogenic electron microscopy images sample individual biomolecules from their conformational landscapes, offering a route to infer the distributions underlying molecular mechanism…
Ultrasensitivity without conformational spread: A mechanical origin for non-equilibrium cooperativity in the bacterial flagellar motor
Henry H. Mattingly, Yuhai Tu
Flagellar motors enable bacteria to navigate their environments by switching rotation direction in response to external cues with high sensitivity. Previous work suggested that ult…
Chemotaxing E. coli do not count single molecules
Henry H. Mattingly, Keita Kamino, Jude Ong +3
Organisms use specialized sensors to measure their environments, but the fundamental principles that determine their accuracy remain largely unknown. In Escherichia coli chemotaxis…
E. coli chemotaxis is information-limited
Henry H. Mattingly, Keita Kamino, Benjamin B. Machta +1
Organisms must acquire and use environmental information to guide their behaviors. However, it is unclear whether and how information quantitatively limits behavioral performance.…