54 citations · 221 across the 34 of their papers we have counts for
8 papers · 1 filter
Automated placement of stereotactic injections using a laser scan of the skull
Margaret Henderson, Vadim Pinskiy, Alexander Tolpygo +3
Stereotactic targeting is a commonly used technique for performing injections in the brains of mice and other animals. The most common method for targeting stereoscopic injections…
Computational neuroanatomy and co-expression of genes in the adult mouse brain, analysis tools for the Allen Brain Atlas
Pascal Grange, Michael Hawrylycz, Partha P. Mitra
We review quantitative methods and software developed to analyze genome-scale, brain-wide spatially-mapped gene-expression data. We expose new methods based on the underlying high-…
What does the Allen Gene Expression Atlas tell us about mouse brain evolution?
Swagatam Mukhopadhyay, Pascal Grange, Anirvan M. Sengupta +1
We use the Allen Gene Expression Atlas (AGEA) and the OMA ortholog dataset to investigate the evolution of mouse-brain neuroanatomy from the standpoint of the molecular evolution o…
Computational neuroanatomy and gene expression: optimal sets of marker genes for brain regions
Pascal Grange, Partha P. Mitra
The three-dimensional data-driven Allen Gene Expression Atlas of the adult mouse brain consists of numerized in-situ hybridization data for thousands of genes, co-registered to the…
Statistical analysis of co-expression properties of sets of genes in the mouse brain
Pascal Grange, Partha P. Mitra
We propose a quantitative method to estimate the statistical properties of sets of genes for which expression data are available and co-registered to a reference atlas of the brain…
A cell-type based model explaining co-expression patterns of genes in the brain
Pascal Grange, Jason Bohland, Hemant Bokil +6
Much of the genome is expressed in the vertebrate brain, with individual genes exhibiting different spatially-varying patterns of expression. These variations are not independent,…
Marker Genes for Anatomical Regions in the Brain: Insights from the Allen Gene Expression Atlas
Pascal Grange, Partha P. Mitra
Quantitative criteria are proposed to identify genes (and sets of genes) whose expression marks a specific brain region (or a set of brain regions). Gene-expression energies, obtai…
Algorithmic choice of coordinates for injections into the brain: encoding a neuroanatomical atlas on a grid
Pascal Grange, Partha P. Mitra
Given an atlas of the brain and a number of injections to be performed in order to map out the connections between parts of the brain, we propose an algorithm to compute the coordi…