91 citations · 130 across the 3 of their papers we have counts for
3 papers
Accurate implementation of leaping in space: The spatial partitioned-leaping algorithm
Krishna A. Iyengar, Leonard A. Harris, Paulette Clancy
There is a great need for accurate and efficient computational approaches that can account for both the discrete and stochastic nature of chemical interactions as well as spatial i…
Quantifying Stochastic Effects in Biochemical Reaction Networks using Partitioned Leaping
Leonard A. Harris, Aaron M. Piccirilli, Emily R. Majusiak +1
"Leaping" methods show great promise for significantly accelerating stochastic simulations of complex biochemical reaction networks. However, few practical applications of leaping…
A "partitioned leaping" approach for multiscale modeling of chemical reaction dynamics
Leonard A. Harris, Paulette Clancy
We present a novel multiscale simulation approach for modeling stochasticity in chemical reaction networks. The approach seamlessly integrates exact-stochastic and "leaping" method…