249 citations · 529 across the 6 of their papers we have counts for
3 papers · 1 filter
An unbiased metric of antiproliferative drug effect in vitro
Leonard A. Harris, Peter L. Frick, Shawn P. Garbett +5
In vitro cell proliferation assays are widely used in pharmacology, molecular biology, and drug discovery. Using theoretical modeling and experimentation, we show that current anti…
BioNetGen 2.2: Advances in Rule-Based Modeling
Leonard A. Harris, Justin S. Hogg, Jose-Juan Tapia +7
BioNetGen is an open-source software package for rule-based modeling of complex biochemical systems. Version 2.2 of the software introduces numerous new features for both model spe…
Exact hybrid particle/population simulation of rule-based models of biochemical systems
Justin S. Hogg, Leonard A. Harris, Lori J. Stover +2
Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad…