27 citations · 53 across the 5 of their papers we have counts for
5 papers
A first-passage-time theory for search and capture of chromosomes by microtubules in mitosis
Manoj Gopalakrishnan, Bindu S. Govindan
The mitotic spindle is an important intermediate structure in eukaryotic cell division, in which each of a pair of duplicated chromosomes is attached through microtubules to centro…
Length control of microtubules by depolymerizing motor proteins
Bindu S. Govindan, Manoj Gopalakrishnan, Debashish Chowdhury
In many intracellular processes, the length distribution of microtubules is controlled by depolymerizing motor proteins. Experiments have shown that, following non-specific binding…
Acid-mediated tumor invasion: How does vasculature affect the growth characteristics?
Bindu. S. Govindan, W. B. Spillman, J. L. Robertson +1
We study the growth of an implanted a-vascular tumor seed in two-dimensions based on a model where the mechanism of invasion is centered on tumor-induced acidification of the micro…
Novel steady state of a microtubule assembly in a confined geometry
Bindu S. Govindan, William. B. Spillman
We study the steady state of an assembly of microtubules in a confined volume, analogous to the situation inside a cell where the cell boundary forms a natural barrier to growth. W…
Stabilization of microtubules due to microtubule-associated proteins: A simple model
Bindu S. Govindan, William B. Spillman
A theoretical model of stabilization of a microtubule assembly due to microtubule-associated-proteins(MAP) is presented. MAPs are assumed to bind to the microtubule filaments, thus…