3 papers
Feasibility of Homomorphic Inference for a Genomic Foundation Model
Christos Galanopoulos, Kimon Antonios Provatas, Ilias Georgakopoulos-Soares
Human genomic sequences can identify individuals, cannot be replaced after disclosure, and are the inputs that genomic foundation models are designed to interpret. We assess whethe…
bioETH-Beacon: A Confidential On-Chain Genomic Beacon with Encrypted Counts, Filters, and Bounded Noise over a Fully Homomorphic EVM
Christos Galanopoulos, Kimon Antonios Provatas, Ilias Georgakopoulos-Soares
The Global Alliance for Genomics and Health (GA4GH) Beacon protocol lets researchers ask whether a genomic variant has been observed in a participating cohort and receive aggregate…
bioETH-PRS: Confidential Polygenic Risk Scoring without a Trusted Evaluator via Fully Homomorphic Encryption on a Programmable Blockchain
Kimon Antonios Provatas, Christos Galanopoulos, Ilias Georgakopoulos-Soares
Polygenic risk scores (PRSs) aggregate genetic effect estimates to predict disease susceptibility, yet clinical deployment often exposes raw genotype data to third-party compute in…