2 papers
physics.bio-ph2026
Electrochemical DNA Hairpin Sensors for Differentiating Small Molecule Intercalation from Minor Groove Binding
Kiara Thompson, Kian Barnes, Saron Yoseph +5
Small molecule double-stranded DNA intercalators have significant potential for therapeutic applications. However, screening for and confirming a drug candidate's intercalative beh…
physics.bio-ph2024
Extending the Operational Lifetime of Nucleic Acid-Based Electrochemical Sensors via Protection Against Competitive Displacement of Oligonucleotides
Vincent Clark, Yuchan Yuan, Frederick Guzman +4
Nucleic acid-based electrochemical sensors (NBEs) have emerged as a promising approach to continuous molecular monitoring in vivo. NBEs consist of electrically conducting gold surf…