activity
20002026
most citedTime and length scales of autocrine signals in three dimensions

32 citations · 57 across the 6 of their papers we have counts for

collaborators

7 papers

cond-mat.stat-mech2026

Modern view of activated rate processes: unidirectional fluxes at equilibrium, correlation functions, and splitting probabilities

Alexander M. Berezhkovskii, Kevin Song, Dmitrii E. Makarov

More than 80 years ago Kramers published a paper calculating how fast a Brownian particle escapes from a potential well over an activation barrier. Since then Kramers' model has be…

physics.chem-ph2024

The significance of fuzzy boundaries of the barrier regions in single-molecule measurements of failed barrier crossing attempts

Alexander M. Berezhkovskii, Dmitrii E. Makarov

A recent experimental study reports on measuring the temporal duration and the spatial extent of failed attempts to cross an activation barrier (i.e., "loops") for a folding transi…

q-bio.QM2022

Blocker effect on diffusion resistance of a membrane channel. Dependence on the blocker geometry

Leonardo Dagdug, Alexei T. Skvortsov, Alexander M. Berezhkovskii +1

Being motivated by recent progress in nanopore sensing, we develop a theory of the effect of large analytes, or blockers, trapped within the nanopore confines, on diffusion flow of…

cond-mat.soft2021

Surface-Facilitated Trapping by Active Sites: From Catalysts to Viruses

Mikita M. Misiura, Alexander M. Berezhkovskii, Sergey M. Bezrukov +1

Trapping by active sites on surfaces plays important roles in various chemical and biological processes, including catalysis, enzymatic reactions, and viral entry into host cells.…

cond-mat.stat-mech2021★ 4 cited

Crowding breaks the forward/backward symmetry of transition times in biased random walks

Jaeoh Shin, Alexander M. Berezhkovskii, Anatoly B. Kolomeisky

Microscopic mechanisms of natural processes are frequently understood in terms of random walk models by analyzing local particle transitions. This is because these models properly…

q-bio.QM2007★ 32 cited

Time and length scales of autocrine signals in three dimensions

Mathieu Coppey, Alexander M. Berezhkovskii, Stuart C. Sealfon +1

A model of autocrine signaling in cultures of suspended cells is developed on the basis of the effective medium approximation. The fraction of autocrine ligands, the mean and distr…

cond-mat.stat-mech2000★ 21 cited

Irreversibble Bimolecular Reactions of Langevin Particles

D. J. Bicout, A. M. Berezhkovskii, Attila Szabo

The reaction A+B --> B is studied when the reactants diffuse in phase space, i.e. their dynamics is described by the Langevin equation. The steady-state rate constants are calculat…