most citedWATCH: A Workflow to Assess Treatment Effect Heterogeneity in Drug Development for Clinical Trial Sponsors

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stat.ME2026

Cluster-induced target shift and synthetic approximation for high-dimensional clustered data

Shangyuan Ye, Cong Zhang, Ying Chen +2

In high-dimensional clustered data, covariates whose distributions differ across clusters can act as proxies for unobserved cluster effects. We show that the marginal-model LASSO i…