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stat.ME2026
Modification and extension of the Bayesian clinical trial design using external data for single-arm and hybrid-controlled trials
Wataru Murasaki, Tomohiro Ohigashi, Ryota Ishii +2
Limited patient availability complicates sample size determination in pediatric clinical trials. Although Bayesian methods incorporating external data offer a solution, rigorously…
stat.ME2026
Posterior Quantification of Borrowing from Multiple Historical Control Data in Bayesian Dynamic Borrowing Methods: A Scoping Review
Tomohiro Ohigashi, Wataru Murasaki, Masahiko Gosho
Bayesian dynamic borrowing methods incorporate historical control data into current clinical trial analyses while allowing the degree of borrowing to depend on the compatibility be…