3 papers
physics.bio-ph2026
Reverse translocation of a nascent polypeptide through the ribosomal exit tunnels
Felipe C. Nepomuceno, Petr Chalupský, Michal Kolář
Before they mature, all known proteins translocate through the ribosomal exit tunnel in a form of extended or partially folded nascent polypeptide. This translocation occurs in the…
physics.bio-ph2024
Three stages of nascent protein translocation through the ribosome exit tunnel
Michal H. Kolář, Hugo Mc Grath, Felipe C. Nepomuceno +1
All proteins in living organisms are produced in ribosomes that facilitate the translation of genetic information into a sequence of amino acid residues. During translation, the ri…
physics.bio-ph2024
Sensitivity of peptide conformational dynamics in carbon nanotubes to directional mechanical forces
Felipe C. Nepomuceno, Michal H. Kolář
In living organisms, proteins and peptides are often under the influence of mechanical forces, especially in confined spaces such as membrane channels, ribosome exit tunnel, or pro…