3 papers
q-bio.GN2026
Informational blueprints reveal condition-dependent gene regulatory architectures
Doruk Efe Gökmen, Rosalind Wenshan Pan, Tom Röschinger +4
While coding regions in the genome have a direct interpretation in terms of protein products, significant fractions are non-coding and yet control essential biological functions. U…
q-bio.GN2025
The Environment-Dependent Regulatory Landscape of the E. coli Genome
Tom Röschinger, Heun Jin Lee, Rosalind Wenshan Pan +7
All cells respond to changes in both their internal milieu and the environment around them through the regulation of their genes. Despite decades of effort, there remain huge gaps…
q-bio.PE2025
Adaptive ratchets and the evolution of molecular complexity
Tom Röschinger, Roberto Morán Tovar, Simone Pompei +1
Biological systems have evolved to amazingly complex states, yet we do not understand in general how evolution operates to generate increasing genetic and functional complexity. Mo…