3 papers
cs.LG2026
Multi-modal transformer for signal classification in nanopore blockade experiments
Sandro Kuppel, Julian Hoßbach, Samuel Tovey +1
Nanopore devices have emerged as powerful tools for single-molecule sensing, with potential for rapid, portable diagnostics. They detect changes in ionic current as analytes enter…
physics.ins-det2026
Latent space mapping of interpretable structural coordinates from stochastic single-molecule signals
Matteo Cartiglia, Sandro Kuppel, Wouter Botermans Wannes Peeters +7
Nanopores are versatile single-molecular sensors, but their utility is fundamentally constrained by stochastic translocation dynamics warping any encoded information. We resolve it…
cs.LG2025
Deep Learning-Driven Peptide Classification in Biological Nanopores
Julian Hoßbach, Samuel Tovey, Sandro Kuppel +3
Nanopore-based single-molecule sensing is a promising route to fast, low-cost disease diagnosis and protein sequencing: as an analyte such as a peptide or protein traverses a nanos…