3 papers
stat.ME2026
Discretization in covariate-adaptive randomization: gains and losses
Zixuan Zhao, Feifang Hu
Covariate-adaptive randomization(CAR) is widely implemented in clinical trials to balance prognostic covariates across treatment arms. Continuous covariates are often discretized i…
stat.AP2026
Systematic Literature Reviews With Two Multi-Agentic Systems And Human-In-The-Loop
Zexin Ren, Zixuan Zhao, Qiyun Li +9
Systematic literature review of clinical trials drives regulatory decision-making, but conventional screening and extraction are time-consuming, labor-intensive, and vulnerable to…
stat.AP2025
SynthIPD: training-free synthetic individual patient data generation
Zixuan Zhao, Zexin Ren, Guannan Zhai +4
Individual patient data (IPD) are essential for statistical inference in clinical research. However, privacy concerns, high data-sharing costs, and restrictive access often make IP…