activity
20232026
most citedDiscovery of Critical Thresholds in Mixed Exposures and Estimation of Policy Intervention Effects using Targeted Learning

1 citations · 2 across the 5 of their papers we have counts for

collaborators

5 papers

stat.ME2026

Priority-Standardized Net Benefit: A Stage-Normalized Estimand for Hierarchical Composite Endpoints

David McCoy, John Leopold, Shirley Galbiati +2

Hierarchical composite endpoints analyzed with win statistics are increasingly used when outcomes differ in clinical importance and hard events are too rare to support a single-com…

stat.ME2024

Data-Adaptive Identification of Effect Modifiers through Stochastic Shift Interventions and Cross-Validated Targeted Learning

David McCoy, Wenxin Zhang, Alan Hubbard +2

In epidemiology, identifying subpopulations that are particularly vulnerable to exposures and those who may benefit differently from exposure-reducing interventions is essential. F…

stat.ME2023

Unveiling Causal Mediation Pathways in High-Dimensional Mixed Exposures: A Data-Adaptive Target Parameter Strategy

David B. McCoy, Alan E. Hubbard, Mark van der Laan +1

Mediation analysis in causal inference typically concentrates on one binary exposure, using deterministic interventions to split the average treatment effect into direct and indire…

stat.ME2023★ 1 cited

Semiparametric Discovery and Estimation of Interaction in Mixed Exposures using Stochastic Interventions

David B. McCoy, Alan E. Hubbard, Alejandro Schuler +1

This study introduces a nonparametric definition of interaction and provides an approach to both interaction discovery and efficient estimation of this parameter. Using stochastic…

stat.ME2023★ 1 cited

Discovery of Critical Thresholds in Mixed Exposures and Estimation of Policy Intervention Effects using Targeted Learning

David McCoy, Alan Hubbard, Alejandro Schuler +1

Traditional regulations of chemical exposure tend to focus on single exposures, overlooking the potential amplified toxicity due to multiple concurrent exposures. We are interested…