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math.ST2024
Testing for similarity of dose response in multi-regional clinical trials
Holger Dette, Lukas Koletzko, Frank Bretz
This paper addresses the problem of deciding whether the dose response relationships between subgroups and the full population in a multi-regional trial are similar to each other.…
math.ST2023
Testing equivalence of multinomial distributions -- a constrained bootstrap approach
Patrick Bastian, Holger Dette, Lukas Koletzko
In this paper we develop a novel bootstrap test for the comparison of two multinomial distributions. The two distributions are called {\it equivalent} or {\it similar} if a norm of…