3 papers
stat.ME2026
Finite-sample correction for the covariate-adjusted log-rank test
Pavla Krotka, Dominic Magirr
The covariate-adjusted log-rank test is a novel method for covariate adjustment in randomized trials with time-to-event endpoints, offering guaranteed efficiency gains compared to…
stat.ME2025
On the inclusion of non-concurrent controls in platform trials with an interim analysis
Pavla Krotka, Martin Posch, Marta Bofill Roig
The analysis of platform trials can be enhanced by utilizing non-concurrent controls. Since including this data might also introduce bias in the treatment effect estimators if time…
stat.ME2024
Treatment-control comparisons in platform trials including non-concurrent controls
Marta Bofill Roig, Pavla Krotka, Katharina Hees +5
Shared controls in platform trials comprise concurrent and non-concurrent controls. For a given experimental arm, non-concurrent controls refer to data from patients allocated to t…