2 papers
math.DS2026
Ghost Dynamics in Receptor Signalling Networks: A Fast--Slow Adaptive Extension of Competitive Cancer Inhibition Models
G Manjunath, Roumen Anguelov
Receptor occupancy models quantify inhibition of cancer signalling, often treating target occupancy as a proxy for downstream activity. Although this simplification yields low-dime…
q-bio.QM2022
Quantifying assays: A Modeling tale of variability in cancer therapeutics assessed on cancer cells
Roumen Anguelov, G Manjunath, Avulundiah E Phiri +4
Inhibiting a signalling pathway concerns controlling the cellular processes of a cancer cell's viability, cell division, and death. Assay protocols created to see if the molecular…