4 papers
DNA Methylation Profiling in Melanoma: From Lesion Classification to Therapeutic Stratification
Jana T. Winterstein, Lukas Heinlein, Günter Raddatz +34
DNA methylation provides a stable record of cellular identity, capturing epigenetic programs that distinguish specialized cell states despite a shared genome. Because malignant tra…
Clinical Melanoma Diagnosis with Artificial Intelligence: Insights from a Prospective Multicenter Study
Lukas Heinlein, Roman C. Maron, Achim Hekler +27
Early detection of melanoma, a potentially lethal type of skin cancer with high prevalence worldwide, improves patient prognosis. In retrospective studies, artificial intelligence…
Using Multiple Dermoscopic Photographs of One Lesion Improves Melanoma Classification via Deep Learning: A Prognostic Diagnostic Accuracy Study
Achim Hekler, Roman C. Maron, Sarah Haggenmüller +28
Background: Convolutional neural network (CNN)-based melanoma classifiers face several challenges that limit their usefulness in clinical practice. Objective: To investigate the im…
Dermatologist-like explainable AI enhances trust and confidence in diagnosing melanoma
Tirtha Chanda, Katja Hauser, Sarah Hobelsberger +32
Although artificial intelligence (AI) systems have been shown to improve the accuracy of initial melanoma diagnosis, the lack of transparency in how these systems identify melanoma…