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stat.ME2026
Distributional Balancing with Machine Learning for Clinical Trial Augmentation Using Real-World Data
Zern Ke, Mingshi Cui, Gemma Moran +1
In clinical trials, randomization of treatment and control groups is typically used to ensure the groups have similar covariate distributions on average, resulting in unbiased caus…
stat.ME2026
From Cumulative Weights to Marginal Density Ratios: Per-Protocol Estimation in Sequential Target Trial Emulation
Zern Ke, Mingshi Cui, Feng Dai +3
Sequential target trial emulation evaluates eligibility at multiple baseline times to emulate a sequence of randomized trials using observational data. Estimating per-protocol effe…