A Conditional Structure-Aware Generative Transformer for Multi-Objective Design of m1Ψ-Modified RNA 5' UTRs

Narges Zarnaghinaghsh, Ahmadreza Mofayezi, Byung-Jun Yoon

The 5' untranslated region is a major determinant of translation initiation, and its effect becomes especially important in modified mRNA sequences, where start-codon context, cap-…