157 citations · 598 across the 34 of their papers we have counts for
4 papers · 1 filter
Target search on networks-within-networks with applications to protein-DNA interactions
Lucas Hedström, Seong-Gyu Yang, Ludvig Lizana
We present a novel framework for understanding node target search in systems organized as hierarchical networks-within-networks. Our work generalizes traditional search models on c…
Identifying stable communities in Hi-C data using a multifractal null model
Lucas Hedström, Antón Carcedo Martínez, Ludvig Lizana
Chromosome capture techniques like Hi-C have expanded our understanding of mammalian genome 3D architecture and how it influences gene activity. To analyze Hi-C data sets, research…
Fractal and knot-free chromosomes facilitate nucleoplasmic transport
Yeonghoon Kim, Ludvig Lizana, Jae-Hyung Jeon
Chromosomes in the nucleus assemble into hierarchies of 3D domains that, during interphase, share essential features with a knot-free condensed polymer known as the fractal globule…
Genomic 3D-compartments emerge from unfolding mitotic chromosomes
Kumar Rajendra, Ludvig Lizana, Per Stenberg
The 3D organisation of the genome in interphase cells is not a randomly folded polymer. Rather, experiments show that chromosomes arrange into a network of 3D compartments that cor…