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stat.ME2026
An Improved Minimization Method: Eliminating Shift and Variance Inflation While Maintaining Marginal Balance
Yuhang Tao, Li-Xin Zhang
Pocock and Simon's minimization method is a widely used approach for covariate-adaptive randomization in clinical trials. However, it can exhibit the shift problem under unequal al…
stat.ME2026
Theoretical Properties of Covariate-Adaptive Randomization with a Diverging Number of Covariates
Yuhang Tao, Li-Xin Zhang
Covariate-adaptive randomization procedures are widely used in clinical trials to improve covariate balance. In modern applications, experimenters often have access to many covaria…