92 citations · 181 across the 7 of their papers we have counts for
7 papers
Fast Multivariate Probit Estimation via a Two-Stage Composite Likelihood
Bryan W. Ting, Fred A. Wright, Yi-Hui Zhou
The multivariate probit is popular for modeling correlated binary data, with an attractive balance of flexibility and simplicity. However, considerable challenges remain in computa…
HT-eQTL: Integrative Expression Quantitative Trait Loci Analysis in a Large Number of Human Tissues
Gen Li, Dereje D. Jima, Fred A. Wright +1
Expression quantitative trait loci (eQTL) analysis identifies genetic markers associated with the expression of a gene. Most existing eQTL analyses and methods investigate associat…
Estimation of Interpretable eQTL Effect Sizes Using a Log of Linear Model
John Palowitch, Andrey Shabalin, Yihui Zhou +2
The study of expression Quantitative Trait Loci (eQTL) is an important problem in genomics and biomedicine. While detection (testing) of eQTL associations has been widely studied,…
An Empirical Bayes Approach for Multiple Tissue eQTL Analysis
Gen Li, Andrey A. Shabalin, Ivan Rusyn +2
Expression quantitative trait loci (eQTL) analyses, which identify genetic markers associated with the expression of a gene, are an important tool in the understanding of diseases…
Convergence and prediction of principal component scores in high-dimensional settings
Seunggeun Lee, Fei Zou, Fred A. Wright
A number of settings arise in which it is of interest to predict Principal Component (PC) scores for new observations using data from an initial sample. In this paper, we demonstra…
A geometric interpretation of the permutation -value and its application in eQTL studies
Wei Sun, Fred A. Wright
Permutation -values have been widely used to assess the significance of linkage or association in genetic studies. However, the application in large-scale studies is hindered by…