546 citations · 1.2k across the 35 of their papers we have counts for
5 papers · 1 filter
OPENMENDEL: A Cooperative Programming Project for Statistical Genetics
Hua Zhou, Janet S. Sinsheimer, Christopher A. German +12
Statistical methods for genomewide association studies (GWAS) continue to improve. However, the increasing volume and variety of genetic and genomic data make computational speed a…
Fast Genome-Wide QTL Analysis Using Mendel
Hua Zhou, Jin Zhou, Tao Hu +2
Pedigree GWAS (Option 29) in the current version of the Mendel software is an optimized subroutine for performing large scale genome-wide QTL analysis. This analysis (a) works for…
Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data
Hua Zhou, John Blangero, Thomas D. Dyer +3
Since most analysis software for genome-wide association studies (GWAS) currently exploit only unrelated individuals, there is a need for efficient applications that can handle gen…
Multicategory vertex discriminant analysis for high-dimensional data
Tong Tong Wu, Kenneth Lange
In response to the challenges of data mining, discriminant analysis continues to evolve as a vital branch of statistics. Our recently introduced method of vertex discriminant analy…
Coordinate descent algorithms for lasso penalized regression
Tong Tong Wu, Kenneth Lange
Imposition of a lasso penalty shrinks parameter estimates toward zero and performs continuous model selection. Lasso penalized regression is capable of handling linear regression p…