activity
20082020
most citedAutomated deconvolution of structured mixtures from bulk tumor genomic data

13 citations · 27 across the 7 of their papers we have counts for

collaborators

7 papers

physics.chem-ph2020★ 1 cited

A Diffusion-Based Embedding of the Stochastic Simulation Algorithm in Continuous Space

Marcus Thomas, Russell Schwartz

A variety of simulation methodologies have been used for modeling reaction-diffusion dynamics -- including approaches based on Differential Equations (DE), the Stochastic Simulatio…

q-bio.GN2016★ 13 cited

Automated deconvolution of structured mixtures from bulk tumor genomic data

Theodore Roman, Lu Xie, Russell Schwartz

Motivation: As cancer researchers have come to appreciate the importance of intratumor heterogeneity, much attention has focused on the challenges of accurately profiling heterogen…

q-bio.QM2015

Derivative-free optimization of rate parameters of capsid assembly models from bulk in vitro data

Lu Xie, Gregory R. Smith, Russell Schwartz

The assembly of virus capsids from free coat proteins proceeds by a complicated cascade of association and dissociation steps, the great majority of which cannot be directly experi…

cs.DS2010

Approximate Dynamic Programming using Halfspace Queries and Multiscale Monge decomposition

Gary L. Miller, Richard Peng, Russell Schwartz +1

Let , $P_i \in \field{R}$ for all , be a signal and let be a constant. In this work our goal is to find a function $F:[n]\rightarrow \field{R}$ wh…

q-bio.GN2010★ 2 cited

CGHTRIMMER: Discretizing noisy Array CGH Data

Charalampos E. Tsourakakis, David Tolliver, Maria A. Tsiarli +2

The development of cancer is largely driven by the gain or loss of subsets of the genome, promoting uncontrolled growth or disabling defenses against it. Identifying genomic region…

q-bio.PE2009★ 1 cited

Generalized Buneman pruning for inferring the most parsimonious multi-state phylogeny

Navodit Misra, Guy Blelloch, R. Ravi +1

Accurate reconstruction of phylogenies remains a key challenge in evolutionary biology. Most biologically plausible formulations of the problem are formally NP-hard, with no known…