64 citations · 501 across the 30 of their papers we have counts for
8 papers · 1 filter
Modelling the electrophysiological interactions between human pluripotent cell-derived cardiomyocite grafts and host ventricular tissue
Suran Galappaththige, Vadim N Biktashev, Faisal J Alibhai +1
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are a promising therapy for regenerating myocardium after infarction, but their use is limited by graft-related arrhyt…
Dynamics of cardiac re-entry in micro-CT and serial histological sections based models of mammalian hearts
Girish S. Ramlugun, Belvin Thomas, Vadim N. Biktashev +5
Cardiac re-entry regime of self-organised abnormal synchronisation underlie dangerous arrhythmias and fatal fibrillation. Recent advances in the theory of dissipative vortices, exp…
Mechanisms of vortices termination in the cardiac muscle
D. Hornung, V. N. Biktashev, N. F. Otani +6
We propose a solution to a long standing problem: how to terminate multiple vortices in the heart, when the locations of their cores and their critical time windows are unknown. We…
Evolution of spiral and scroll waves of excitation in a mathematical model of ischaemic border zone
Vadim N. Biktashev, Irina V. Biktasheva, Narine A. Sarvazyan
Abnormal electrical activity from the boundaries of ischemic cardiac tissue is recognized as one of the major causes in generation of ischemia-reperfusion arrhythmias. Here we pres…
Asymptotics of conduction velocity restitution in models of electrical excitation in the heart
R. D. Simitev, V. N. Biktashev
We extend a non-Tikhonov asymptotic embedding, proposed earlier, for calculation of conduction velocity restitution curves in ionic models of cardiac excitability. Conduction veloc…
Low energy defibrillation in human cardiac tissue: a simulation study
S. W. Morgan, G. Plank, I. V. Biktasheva +1
We aim to assess the effectiveness of feedback controlled resonant drift pacing as a method for low energy defibrillation. Antitachycardia pacing is the only low energy defibrillat…