112 citations · 264 across the 17 of their papers we have counts for
4 papers · 1 filter
CARB: A Covariate-Assessed Robust Borrowing Strategy with Literature-Informed Prior Weights for External Data
Jinping Liang, Guannan Gong, Satrajit Roychoudhury +1
Borrowing external control data can improve the efficiency of clinical trials, particularly when patient accrual is difficult. A persistent challenge is how to prespecify the degre…
Dynamic Prediction of the Target Survival Time in Metastatic Solid Tumor Cancer Clinical Trials
Sidi Wang, Kelley Kidwell, Bo Huang +1
Overall survival (OS) is the gold standard for assessing patient benefit and cost-effectiveness of new cancer drugs. However, it is often difficult to use OS as the primary endpoin…
Learning from Literature: Integrating LLMs and Bayesian Hierarchical Modeling for Oncology Trial Design
Guannan Gong, Satrajit Roychoudhury, Allison Meisner +3
Designing modern oncology trials requires synthesizing evidence from prior studies to inform hypothesis generation and sample size determination. Trial designs based on incomplete…
On regional treatment effect assessment using robust MAP priors
Xin Zhang, Hui Zhang, Satrajit Roychoudhury
Bayesian dynamic borrowing has become an increasingly important tool for evaluating the consistency of regional treatment effects which is a key requirement for local regulatory ap…