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20082021
most citedMultiple tests of association with biological annotation metadata

18 citations · 48 across the 12 of their papers we have counts for

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9 papers · 1 filter

math.ST2021

Continuous-time targeted minimum loss-based estimation of intervention-specific mean outcomes

Helene C. Rytgaard, Thomas A. Gerds, Mark J. van der Laan

This paper studies the generalization of the targeted minimum loss-based estimation (TMLE) framework to estimation of effects of time-varying interventions in settings where both i…

math.ST2021

Adaptive Sequential Design for a Single Time-Series

Ivana Malenica, Aurelien Bibaut, Mark J. van der Laan

The current work is motivated by the need for robust statistical methods for precision medicine; as such, we address the need for statistical methods that provide actionable infere…

math.ST20214 cited

Sequential causal inference in a single world of connected units

Aurelien Bibaut, Maya Petersen, Nikos Vlassis +2

We consider adaptive designs for a trial involving N individuals that we follow along T time steps. We allow for the variables of one individual to depend on its past and on the pa…

math.ST2021

Higher Order Targeted Maximum Likelihood Estimation

Mark van der Laan, Zeyi Wang, Lars van der Laan

Asymptotic efficiency of targeted maximum likelihood estimators (TMLE) of target features of the data distribution relies on a a second order remainder being asymptotically negligi…

math.ST20201 cited

Sufficient and insufficient conditions for the stochastic convergence of Cesàro means

Aurélien F. Bibaut, Alex Luedtke, Mark J. van der Laan

We study the stochastic convergence of the Cesàro mean of a sequence of random variables. These arise naturally in statistical problems that have a sequential component, where the…

math.ST2019

Fast rates for empirical risk minimization over càdlàg functions with bounded sectional variation norm

Aurélien F. Bibaut, Mark J. van der Laan

Empirical risk minimization over classes functions that are bounded for some version of the variation norm has a long history, starting with Total Variation Denoising (Rudin et al.…