77 citations · 142 across the 4 of their papers we have counts for
4 papers
Modeling the formation of in vitro filopodia
K. -C. Lee, A. Gopinathan, J. M. Schwarz
Filopodia are bundles of actin filaments that extend out ahead of the leading edge of a crawling cell to probe its upcoming environment. {\it In vitro} experiments [D. Vignjevic {\…
New Proposed Mechanism of Actin-Polymerization-Driven Motility
Kun-Chun Lee, Andrea J. Liu
We present the first numerical simulation of actin-driven propulsion by elastic filaments. Specifically, we use a Brownian dynamics formulation of the dendritic nucleation model of…
Branching, Capping, and Severing in Dynamic Actin Structures
Ajay Gopinathan, Kun-Chun Lee, J. M. Schwarz +1
Branched actin networks at the leading edge of a crawling cell evolve via protein-regulated processes such as polymerization, depolymerization, capping, branching, and severing. A…
Effect of Mono- and Multivalent Salts on Angle-dependent Attractions between Charged Rods
Kun-Chun Lee, Itamar Borukhov, William M. Gelbart +2
Using molecular dynamics simulations we examine the effective interactions between two like-charged rods as a function of angle and separation. In particular, we determine how the…