5 papers
Development of a Proton Therapy Research Beamline with FLASH and Minibeam Capabilities at the 18 MeV Bern Medical Cyclotron
Eva Kasanda, Lars Eggiman, Thierry Stammbach +10
Advanced radiotherapy approaches such as FLASH irradiation and spatially fractionated radiotherapy (SFRT) show potential to improve the therapeutic ratio, yet their biological mech…
Terbium-149 PET/CT: First Quantitative Imaging with a Clinical Long-Axial Field-of-View Scanner
Lorenzo Mercolli, Pascal V. Grundler, Anzhelika N. Moiseeva +4
Introduction: Terbium-149 (Tb) is a promising radionuclide for targeted therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low…
Non-Destructive Beam Monitoring via Secondary Radiation Detection with Ce-Doped Silica Fibers
Alexander Gottstein, Pierluigi Casolaro, Gaia Dellepiane +7
Non-destructive beam diagnostics are essential for low-energy medical cyclotrons, where even thin interceptive devices can severely degrade beam quality. We investigate an external…
Beam Energy Measurement using a Bayesian Approach with the Stacked Foil Method
Alexander Gottstein, Lorenzo Mercolli, Eva Kasanda +7
We present a practical method to measure the energy of proton beams at a medical cyclotron using the stacked foil technique in combination with a Bayesian inference method. By meas…
First Positronium Lifetime Imaging with Scandium-44 on a Long Axial Field-of-view PET/CT
Lorenzo Mercolli, William M. Steinberger, Pascal V. Grundler +12
Purpose: 44Sc has been successfully produced, synthesized, labeled and first-in-human studies were conducted some years ago. The decay properties of 44Sc, together with being close…