120 citations · 446 across the 4 of their papers we have counts for
4 papers
Mechanisms of kinetic trapping in self-assembly and phase transformation
Michael F. Hagan, Oren M. Elrad, Robert L. Jack
In self-assembly processes, kinetic trapping effects often hinder the formation of thermodynamically stable ordered states. In a model of viral capsid assembly and in the phase tra…
Encapsulation of a polymer by an icosahedral virus
Oren M. Elrad, Michael F. Hagan
The coat proteins of many viruses spontaneously form icosahedral capsids around nucleic acids or other polymers. Elucidating the role of the packaged polymer in capsid formation co…
Understanding the Concentration Dependence of Viral Capsid Assembly Kinetics - the Origin of the Lag Time and Identifying the Critical Nucleus Size
Michael F. Hagan
The kinetics for the assembly of viral proteins into a population of capsids can be measured in vitro with size exclusion chromatography or dynamic light scattering, but extracting…
Mechanisms of Size Control and Polymorphism in Viral Capsid Assembly
Oren M. Elrad, Michael F. Hagan
We simulate the assembly dynamics of icosahedral capsids from subunits that interconvert between different conformations (or quasi-equivalent states). The simulations identify mech…