4 papers
Physiology and Anatomy Aware Inverse Inference of Myocardial Infarction for Cardiac Digital Twin
Mengxiao Wang, Yilin Lyu, Julia Camps +6
Accurate localization of myocardial infarction is essential for risk stratification. While LGE-MRI remains the gold standard, it is resource-intensive. Integrating cine MRI with EC…
Simulation-based digital twinning of activation and repolarisation sequences from the ECG across healthy and diseased hearts
James A Coleman, Julia Camps, Abdallah I Hasaballa +1
Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies,…
An Automated Computational Pipeline for Generating Large-Scale Cohorts of Patient-Specific Ventricular Models in Electromechanical In Silico Trials
Ruben Doste, Julia Camps, Zhinuo Jenny Wang +8
In recent years, human in silico trials have gained significant traction as a powerful approach to evaluate the effects of drugs, clinical interventions, and medical devices. In si…
Personalized Topology-Informed Localization of Standard 12-Lead ECG Electrode Placement from Incomplete Cardiac MRIs for Efficient Cardiac Digital Twins
Lei Li, Hannah Smith, Yilin Lyu +5
Cardiac digital twins (CDTs) offer personalized in-silico cardiac representations for the inference of multi-scale properties tied to cardiac mechanisms. The creation of CDTs requi…