410 citations · 1.7k across the 23 of their papers we have counts for
4 papers · 1 filter
How the DNA sequence affects the Hill curve of transcriptional response
M. Sheinman, Y. Kafri
The Hill coefficient is often used as a direct measure of the cooperativity of binding processes. It is an essential tool for probing properties of reactions in many biochemical sy…
Length-Controlled Elasticity in 3D Fiber Networks
C. P. Broedersz, M. Sheinman, F. C. MacKintosh
We present a model for disordered 3D fiber networks to study their linear and nonlinear elasticity over a wide range of network densities and fiber lengths. In contrast to previous…
Nonlinear effective medium theory of disordered spring networks
M. Sheinman, C. P. Broedersz, F. C. MacKintosh
Disordered soft materials, such as fibrous networks in biological contexts exhibit a nonlinear elastic response. We study such nonlinear behavior with a minimal model for networks…
Classes of fast and specific search mechanisms for proteins on DNA
M. Sheinman, O. Bénichou, Y. Kafri +1
Problems of search and recognition appear over different scales in biological systems. In this review we focus on the challenges posed by interactions between proteins, in particul…