72 citations · 249 across the 12 of their papers we have counts for
3 papers · 1 filter
Stable developmental patterns of gene expression without morphogen gradients
Maciej Majka, Nils B. Becker, Pieter Rein ten Wolde +2
Gene expression patterns (GEPs) are established by cross-regulating target genes that interpret morphogen gradients. However, as development progresses, morphogen activity is reduc…
Trade-offs between cost and information in cellular prediction
Age J. Tjalma, Vahe Galstyan, Jeroen Goedhart +3
Living cells can leverage correlations in environmental fluctuations to predict the future environment and mount a response ahead of time. To this end, cells need to encode the pas…
Quantifying fluctuations in reversible enzymatic cycles and clocks
Harmen Wierenga, Pieter Rein ten Wolde, Nils B. Becker
Biochemical reactions are fundamentally noisy at a molecular scale. This limits the precision of reaction networks, but also allows fluctuation measurements which may reveal the st…