4 papers
ProtDBench: A Unified Benchmark of Protein Binder Design and Evaluation
Cong Liu, Milong Ren, Jiaqi Guan +4
Recent advances in de novo protein binder design have enabled increasing experimental validation, yet reported in silico metrics remain difficult to interpret or compare across stu…
A-CODE: Fully Atomic Protein Co-Design with Unified Multimodal Diffusion
Chaoran Cheng, Jiaqi Guan, Milong Ren +5
We present A-CODE, a fully atomic unified one-stage protein co-design model that simultaneously refines discrete atom types and continuous atom coordinates. Unlike predominant two-…
Protenix-Mini+: efficient structure prediction model with scalable pairformer
Bo Qiang, Chengyue Gong, Xinshi Chen +2
Lightweight inference is critical for biomolecular structure prediction and downstream tasks, enabling efficient real-world deployment and inference-time scaling for large-scale ap…
Protenix-Mini: Efficient Structure Predictor via Compact Architecture, Few-Step Diffusion and Switchable pLM
Chengyue Gong, Xinshi Chen, Yuxuan Zhang +3
Lightweight inference is critical for biomolecular structure prediction and other downstream tasks, enabling efficient real-world deployment and inference-time scaling for large-sc…