4 papers
Memory-driven topological ordering during the transition from dormant to migrating epithelia
Richard Ho, Anna LÃ¥ng, Emma LÃ¥ng +2
Transitions from quiescence to collective migration in epithelia underlie wound healing and cancer invasion, yet their physical origin remains poorly understood. Here we show that…
Euler-Maruyama method for non-Wiener processes
Richard D. J. G. Ho
Descriptions of complex physical or biological systems often include stochastic contributions, and these are commonly simulated using Wiener processes. In many cases however, non-G…
Spontaneous elongation of 3D gastruloids from local cell polarity alignment
Richard D. J. G. Ho, Endre J. L. Mossige, Sergei Ponomartcev +6
Gastruloids are 3D stem cell aggregate models for early embryogenesis that provide a unique platform to study how collective cell dynamics drive tissue symmetry breaking and axial…
Emergent cell migration from cell shape deformations and T1 transitions
Harish P. Jain, Richard D. J. G. Ho, Luiza Angheluta
T1 transitions, which are localised cell rearrangements, play an important role in the fluidization of epithelial monolayers. Using a multi-phase field model and an active elastic…