78 citations · 231 across the 10 of their papers we have counts for
3 papers · 1 filter
Prediction of kinase inhibitor response using activity profiling, in-vitro screening, and elastic net regression
Trish Tran, Edison Ong, Andrew P. Hodges +2
Many kinase inhibitors have been approved as cancer therapies. Recently, libraries of kinase inhibitors have been extensively profiled, thus providing a map of the strength of acti…
Search algorithms as a framework for the optimization of drug combinations
Diego Calzolari, Stefania Bruschi, Laurence Coquin +5
Combination therapies are often needed for effective clinical outcomes in the management of complex diseases, but presently they are generally based on empirical clinical experienc…
Selective control of the apoptosis signaling network in heterogeneous cell populations
Diego Calzolari, Giovanni Paternostro, Patrick L. Harrington +2
Selective control in a population is the ability to control a member of the population while leaving the other members relatively unaffected. The concept of selective control is de…