1.1k citations · 2.6k across the 24 of their papers we have counts for
23 papers
Evaluation of tools for differential gene expression analysis by RNA-seq on a 48 biological replicate experiment
Nicholas J. Schurch, Pieta Schofield, Marek Gierliński +9
An RNA-seq experiment with 48 biological replicates in each of 2 conditions was performed to determine the number of biological replicates () required, and to identify the mos…
Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment
Marek Gierliński, Christian Cole, Pietà Schofield +9
High-throughput RNA sequencing (RNA-seq) is now the standard method to determine differential gene expression. Identifying differentially expressed genes crucially depends on estim…
Improved annotation of 3-prime untranslated regions and complex loci by combination of strand-specific Direct RNA Sequencing, RNA-seq and ESTs
Nick Schurch, Christian Cole, Alexander Sherstnev +7
The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct annotation is particularly important when interpreting…
The location and kinematics of the coronal-line emitting regions in AGN
J. R. Mullaney, M. J. Ward, C. Done +2
We use the photoionisation code Cloudy to determine both the location and the kinematics of the optical forbidden, high ionisation line (hereafter, FHIL) emitting gas in the narrow…
The impact of accretion disk winds on the X-ray spectrum of AGN: Part 2 - XSCORT + Hydrodynamic Simulations
N. J. Schurch, C. Done, D. Proga
abridged: We use XSCORT, together with the hydrodynamic accretion disc wind simulation from Proga & Kallman (2004), to calculate the impact that the accretion disk wind has on the…
Integral and Rxte/Asm Observations on Igr J17098-3628
Yu-Peng Chen, Shu Zhang, Nick Schurch +5
To probe further the possible nature of the unidentified source IGR J17098-3628, we have carried out a detailed analysis of its long-term time variability as monitored by RXTE/ASM,…