52 citations · 60 across the 6 of their papers we have counts for
3 papers · 1 filter
Scanning a Poisson Random Field for Local Signals
Nancy R. Zhang, Benjamin Yakir, Charlie L. Xia +1
The detection of local genomic signals using high-throughput DNA sequencing data can be cast as a problem of scanning a Poisson random field for local changes in the rate of the pr…
Change-point model on nonhomogeneous Poisson processes with application in copy number profiling by next-generation DNA sequencing
Jeremy J. Shen, Nancy R. Zhang
We propose a flexible change-point model for inhomogeneous Poisson Processes, which arise naturally from next-generation DNA sequencing, and derive score and generalized likelihood…
Importance Sampling of Word Patterns in DNA and Protein Sequences
Hock Peng Chan, Nancy R. Zhang, Louis H. Y. Chen
Monte Carlo methods can provide accurate p-value estimates of word counting test statistics and are easy to implement. They are especially attractive when an asymptotic theory is a…