5 papers
DNA end tethering through break-induced DNA--protein condensation
Rakesh Das, Tarun Mascarenhas, Nagaraja Chappidi +2
Cells deploy robust mechanisms to repair DNA damage, safeguarding genomic stability and cellular health, but the physical principles underlying these processes remain incompletely…
Hydrodynamic theory of chemically active emulsions
Efe Ilker, Kathrin Laxhuber, Jean-Francois Joanny +1
We present a systematic theory of chemically active emulsions in the hydrodynamic limit by constructing a thermodynamically consistent framework in which the equilibrium is broken…
Physical Approaches to Metabolic Scaling in Living Systems
Efe Ilker, Michael Hinczewski, Xingbo Yang +1
Living systems continuously transform matter and energy through the chemical processes that constitute their metabolism. The overall metabolic rate of an organism correlates positi…
In vitro binding energies capture Klf4 occupancy across the human genome
Anne Schwager, Jonas Neipel, Yahor Savich +4
Transcription factors (TFs) regulate gene expression by binding to specific genomic loci determined by DNA sequence. Their sequence specificity is commonly summarized by a consensu…
A Model for Self-Organized Growth, Branching, and Allometric Scaling of the Planarian Gut
Christian Hanauer, Amrutha Palavalli, Baiqun An +3
The growth and scaling of organs is a fundamental aspect of animal development. However, how organs grow to the right size and shape required by physiological demands, remains larg…