7 papers
Relative Translation Invariant Wasserstein Distance
Binshuai Wang, Qiwei Di, Ming Yin +3
Motivated by the Bures distance, we introduce a new family of distances, \emph{relative translation invariant Wasserstein distances}, denoted by , as an extension of the clas…
CRISPR-GPT for Agentic Automation of Gene-editing Experiments
Yuanhao Qu, Kaixuan Huang, Ming Yin +11
The introduction of genome engineering technology has transformed biomedical research, making it possible to make precise changes to genetic information. However, creating an effic…
Toward Scientific Reasoning in LLMs: Training from Expert Discussions via Reinforcement Learning
Ming Yin, Yuanhao Qu, Ling Yang +2
We investigate how to teach large language models (LLMs) to perform scientific reasoning by leveraging expert discussions as a learning signal. Focusing on the genomics domain, we…
ProtFlow: Fast Protein Sequence Design via Flow Matching on Compressed Protein Language Model Embeddings
Zitai Kong, Yiheng Zhu, Yinlong Xu +7
The design of protein sequences with desired functionalities is a fundamental task in protein engineering. Deep generative methods, such as autoregressive models and diffusion mode…
MATH-Perturb: Benchmarking LLMs' Math Reasoning Abilities against Hard Perturbations
Kaixuan Huang, Jiacheng Guo, Zihao Li +15
Large language models have demonstrated impressive performance on challenging mathematical reasoning tasks, which has triggered the discussion of whether the performance is achieve…
Fast Best-of-N Decoding via Speculative Rejection
Hanshi Sun, Momin Haider, Ruiqi Zhang +6
The safe and effective deployment of Large Language Models (LLMs) involves a critical step called alignment, which ensures that the model's responses are in accordance with human p…