activity
20152026
most citedThe effect of non-reversibility on inferring rooted phylogenies

3 citations · 4 across the 6 of their papers we have counts for

collaborators

6 papers

stat.ME2026

Comparing Bayesian Dynamic Borrowing and Synthetic Control Methods: Apples to Oranges?

Nicole Cizauskas, Foteini Strimenopoulou, Svetlana S. Cherlin +1

Bayesian dynamic borrowing (BDB) and synthetic control methods (SCM) are strategies to incorporate historical data in clinical trial design when control recruitment is a challenge.…

stat.ME2024

Augmented Binary Method for Basket Trials (ABBA)

Svetlana Cherlin, James M S Wason

In several clinical areas, traditional clinical trials often use a responder outcome, a composite endpoint that involves dichotomising a continuous measure. An augmented binary met…

stat.AP2023

Utilising high-dimensional data in randomised clinical trials: a review of methods and practice

Svetlana Cherlin, Theophile Bigirumurame, Michael J Grayling +6

Introduction: Even in effectively conducted randomised trials, the probability of a successful study remains relatively low. With recent advances in the next-generation sequencing…

stat.ME2021★ 1 cited

Cross-validated risk scores adaptive enrichment (CADEN) design

Svetlana Cherlin, James M S Wason

We propose a Cross-validated ADaptive ENrichment design (CADEN) in which a trial population is enriched with a subpopulation of patients who are predicted to benefit from the treat…

stat.ME2020

Developing a predictive signature for two trial endpoints using the cross-validated risk scores method

Svetlana Cherlin, James M. S. Wason

The existing cross-validated risk scores (CVRS) design has been proposed for developing and testing the efficacy of a treatment in a high-efficacy patient group (the sensitive grou…

q-bio.PE2015★ 3 cited

The effect of non-reversibility on inferring rooted phylogenies

S. Cherlin, T. M. W. Nye, S. E. Heaps +3

Most phylogenetic models assume that the evolutionary process is stationary and reversible. As a result, the root of the tree cannot be inferred as part of the analysis because the…