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physics.bio-ph2024
Alpha helices are more evolutionarily robust to environmental perturbations than beta sheets: Bayesian learning and statistical mechanics for protein evolution
Tomoei Takahashi, George Chikenji, Kei Tokita +1
How typical elements that shape organisms, such as protein secondary structures, have evolved, or how evolutionarily susceptible/resistant they are to environmental changes, are si…
physics.bio-ph2020★ 6 cited
Lattice protein design using Bayesian learning
Tomoei Takahashi, George Chikenji, Kei Tokita
Protein design is the inverse approach of the three-dimensional (3D) structure prediction for elucidating the relationship between the 3D structures and amino acid sequences. In ge…