1 citations · 1 across the 1 of their papers we have counts for
2 papers
q-bio.BM2026★ 1 cited
JEDEL: Zero-Shot DNA-Encoded Library Design for Early-Stage Drug Discovery
Zygimantas Jocys, Zhanxing Zhu, Henriette M. G. Willems +1
We present JEDEL, a framework for generating synthesis-ready DNA-encoded libraries (DELs) directly from three-dimensional pharmacophore representations of active ligands. JEDEL is…
cs.LG2024
SynthFormer: Equivariant Pharmacophore-based Generation of Synthesizable Molecules for Ligand-Based Drug Design
Zygimantas Jocys, Zhanxing Zhu, Henriette M. G. Willems +1
Drug discovery is a complex, resource-intensive process requiring significant time and cost to bring new medicines to patients. Many generative models aim to accelerate drug discov…